ONDASON Injection

Ondansetron USP

Composition : Ondansetron USP 2mg/ml Injection.

Indication : It is used for the prevention of nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy. It is also used for the prevention of postoperative nausea and/or vomiting.

Dosage and administration :

1) Prevention of Nausea and Vomiting Associated with Initial and Repeat Courses of Emetogenic Chemotherapy : Adults : 32mg single dose infused over 15 minutes by diluting with 50ml saline (5% dextrose or 0.9% Nacl) 30 minutes before starting chemotherapy. Alternatively, three dose of 0.15mg/kg body weight. The first dose is infused over 15 minutes beginning 30 minutes before the starting chemotherapy. Subsequent doses (0.15mg/kg) are administered 4 and 8 hours after the first dose of administration. Pediatric : 6months onwards: three dose of 0.15mg/kg body weight. The first dose is infused over 15 minutes beginning 30 minutes before starting moderately to highly emetogenic chemotherapy. Subsequent doses (0.15mg/kg) are administered 4 and 8 hours after the first dose of administration. 2) Prevention of Postoperative Nausea and Vomiting: Adults: Undiluted 4mg intravenously or intramuscularly immediately before induction of anesthesia. The rate of administration should not be less than 30 seconds, preferably over 2 to 5 minutes. Alternatively, the dose can be administered post-operatively if the patient experiences nausea and/or vomiting shortly after surgery. Pediatrics (1 months to 12 years) : Weighing less than 40kg: 0.1mg/kg body weight in a single dose. Weighing more than 40kg: 4mg single dose. The dose should be immediately before induction of anesthesia. The rate of administration should not be less than 30 seconds, preferably over 2 to 5 minutes. Alternatively, the dose can be administered post-operatively if the patient experiences nausea and/or vomiting shortly after surgery. Or, as directed by the registered physician.

Pregnancy and lactation : Pregnancy Category B by FDA.

Packing : Ondason Injection (IV/IM) : 1 x 3's ampoules in blister pack.

Prescribing Description

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