Water insolubility has always been a key obstacle in pharmaceutical formulation, affecting formulation stability and drug bioavailability. Approaches for achieving complete dissolution. Nanoparticle is a general challenge for today's technology and the near future observations of science Nanoparticles cover mostly all types of sciences and manufacturing technologies. The properties of this particle are flying over today scientific barriers and have passed the limitations of conventional sciences. This is the reason why nanoparticles have been evaluated for the use in many fields. Drug International Ltd. approached by the art of exploring the most advanced research in the field of nano-scale particles, preparation techniques and the way of reaching their destination.