Esomeprazole USP MUPS
Composition: Pronex-MUPS: Each MUPS (Multiple-Unit Pellet System) tablet contains Esomeprazole USP 20mg as Esomeprazole Magnesium Trihydrate USP.
Indications: This tablet is used in the treatment of Gastroesophageal Reflux Disease (GERD). Also used to reduce the risk of NSAID associated gastric ulcer, H.pylorieradication (triple therapy), duodenal and qastric ulcer and Zollinger-Ellison Syndrome.
Dosage and administration: Adult from ageof 18 Erosive Reflux Oesophagitis : Therecommended dosage is one 20mg once daily before meal, given for 4 weeks. For those patients not fully healed after the initial course, healing usually occurs during a furher 4 weeks treatment. Patients with Reflux OesophagitisRefractory to Other Therapy: The recommended dosage is 40mg once daily before meal. Healing usually occurs within 8 weeks. Duodenal Ulcer: The usual dose is one 20mg once daily, before meal for 4 weeks. In severe cases the dose may be increased to 40mg once daily before meal. Gastric Ulcer: The usual dose is one 20mg tablet once daily before meal for 8 weeks. In severe cases, the dose may be increased to 40mg tablet once daily. Long-term maintenance treatment with is not recommended. Zollinger-Ellison Syndrome: The recommended initial dosage is 60mg (40mg + 20mg) once daily before meal. The dosage should be adjusted individually and treatment continued as long as clinically indicated. More than 90% of patients with severe disease and inadequate response to other therapies have been effectively controlled on doses of 20mg 120mg daily, With doses above 80mg daily, the dose should be divided and given twice daily. Elderly: Dose adjustment is not required in the elderly.Or,as directed by the registered physicians.