Voriconazole
Composition: Each
vial contains Voriconazole USP 200mg sterile lyophilized powder.
Indications: It
is indicated for the treatment of adults and pediatric patients 2 years of age
and older with: Invasive aspergillosis, Candidemia in non-neutropenics and
other deep tissue Candida infections, Esophageal candidiasis, Serious fungal
infections caused by Scedosporium apiospermum and Fusarium species including
Fusarium solani, in patients intolerant of, or refractory to, other therapy.
Dosage and
Administration: For pediatric patients
aged 12 to 14 years weighing greater than or equal to 50kg and those aged 15
years and older regardless of body weight use adult dosage. Or, as directed by the registered physician. Reconstitution: Voriconazole injection
requires reconstitution and dilution prior to administration as intravenous
infusion. The powder is reconstituted with 19 ml of water for injection to
obtain an extractable volume of 20ml of clear concentrate containing 10mg/ml of
voriconazole. Shake the vial until all the powder is dissolved. This medicinal product is for single use only and any unused
solution should be discarded.
Use in Pregnancy and
Lactation: There are no adequate data on the use of
Voriconazole in pregnant women available. Voriconazole must not be used during
pregnancy unless the benefit to the mother clearly outweighs the potential risk
to the foetus. The excretion of Voriconazole into breast milk has not been
investigated.
Packing: Vorizol-200 Injection (IV): Each combipack contains 1 vial of Voriconazole USP 200mg sterile lyophilized powder, with two ampoules of 10ml Water for Injection BP.
